Romain Koszul Research Group
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Recent work
Spatial reorganization of telomeres in yeast quiescence long-lived cells (Guidi et al., Genome Biology, in press; with Angela Taddei lab)
Condensin- and Replication-Mediated Bacterial Chromosome Folding and Origin Condensation Revealed by Hi-C and Super-resolution Imaging (Marbouty, le Gall et al., Molecular Cell, 2015; with Marcelo Nollmann lab)
meta3C is an integrated approach to metagenomic analysis, allowing the
de novo
assembly, scaffolding and 3D characterization of unknown genomes from complex mix of species (Marbouty
et al.
, eLife, 2014)
GRAAL is a powerful scaffolding program that exploits chromosome contacts data and polymer physics predictions to compute the most likely structure of a genome (Marie-Nelly
et al.
, Nature Commun., 2014)
As members of the international consortium Saccharomyces cerevisiae 2.0 led by Pr. Jef Boeke (NYU), we contributed to the analysis of the first synthetic eukaryotic chromosome (Annaluru
et al.
, Science, 2014).